Korean J Parasitol.  1988 Mar;26(1):27-32. 10.3347/kjp.1988.26.1.27.

Comparative evaluation of indirect immunofluorescent antibody test with enzyme-linked immunosorbent assay in serodiagnosis of human neurocysticercosis

• Eom KS
• Cho SY
• Rim HJ

• KMID: 1714953
• DOI: http://doi.org/10.3347/kjp.1988.26.1.27

Abstract

The applicability of indirect immunofluorescent antibody test (IFAT) was compared with enzyme-linked immunosorbent assay (ELISA) in sera from 163 cases of confirmed neurocysticercosis, 101 other neurologic and parasitic diseases and 100 normal controls. As antigen, frozen sections of a Taenia solium metacestode from a human brain was used in IFAT and cystic fluid was used in ELISA. For the detection of specific IgG antibody, IFAT was equally sensitive (89. 6%) and specific (85. l%) as ELISA. The antibody titers by IFAT were correspondingly increased with mean absorbance of ELISA. The corresponding rate of positivity in the two techniques was 90.8%. Except for the difficulty in detecting antibodies in cerebrospinal fluid (CSF), IFAT was concluded to be very useful for the serodiagnosis of human neurocysticercosis.

MeSH Terms

parasitology-helminth-cestoda
Taenia solium
cysticercus
enzyme-linked immunosorbent assay
cerebrospinal fluid
brain
IgG
immunofluorescence
immunology