Korean J Radiol.  2013 Jun;14(3):391-394. 10.3348/kjr.2013.14.3.391.

Subcutaneous Panniculitis-Like T-Cell Lymphoma of the Breast

Affiliations
  • 1Department of Radiology, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun 519-763, Korea. nico1220@dreamwiz.com
  • 2Department of Radiology, Chonnam National University Hospital, Gwangju 501-757, Korea.
  • 3Department of Surgery, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun 519-763, Korea.
  • 4Department of Pathology, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun 519-763, Korea.

Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare subtype of cutaneous lymphoma. There have been a few case reports describing the radiologic imaging findings of SPTCL. We report a case of SPTCL, rarely presented with a breast mass. Here, we review her clinical history and radiologic (mammography and ultrasound) findings.

Keyword

Subcutaneous panniculitis-like T-cell lymphoma; Breast; Mammography; Ultrasound

MeSH Terms

Adult
Breast Neoplasms/*pathology/radiography/ultrasonography
Female
Humans
Lymphoma, T-Cell/*pathology/radiography/ultrasonography
Mammography
Panniculitis/*pathology/radiography/ultrasonography
Rare Diseases/*pathology/radiography/ultrasonography
Skin Neoplasms/*pathology/radiography/ultrastructure

Figure

  • Fig. 1 Subcutaneous panniculitis-like T-cell lymphoma of breast in 43-year-old woman. A. Mediolateral oblique mammographic view of left breast shows 5-cm, increased opacity with indistinct margin in upper portion of left breast. There are no calcifications or architectural distortion. Craniocaudal mammographic view of left breast shows no abnormal finding (not shown). B. Sonography of left breast shows diffuse hyperechogenicity with poorly defined margin in subcutaneous fat layer of left upper inner breast. C, D. Microscopic examination shows infiltration of neoplastic lymphoid cells into subcutaneous tissue (arrows), but not into overlying dermis and epidermis in low-power view (C, H&E staining, × 20) and focal rimming of adipocytes by atypical lymphocytes and phagocytic macrophages in subcutaneous tissue in high-power view (D, H&E staining, × 400). E. Immunohistochemical stain shows rimming of individual fat spaces by tumor cells with staining for CD8 (× 400).


Reference

1. Gonzalez CL, Medeiros LJ, Braziel RM, Jaffe ES. T-cell lymphoma involving subcutaneous tissue. A clinicopathologic entity commonly associated with hemophagocytic syndrome. Am J Surg Pathol. 1991. 15:17–27.
2. Willemze R, Jaffe ES, Burg G, Cerroni L, Berti E, Swerdlow SH, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005. 105:3768–3785.
3. Willemze R, Jansen PM, Cerroni L, Berti E, Santucci M, Assaf C, et al. Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: an EORTC Cutaneous Lymphoma Group Study of 83 cases. Blood. 2008. 111:838–845.
4. Sy AN, Lam TP, Khoo US. Subcutaneous panniculitislike T-cell lymphoma appearing as a breast mass: a difficult and challenging case appearing at an unusual site. J Ultrasound Med. 2005. 24:1453–1460.
5. Schramm N, Pfluger T, Reiser MF, Berger F. Subcutaneous panniculitis-like T-cell lymphoma with breast involvement: functional and morphological imaging findings. Br J Radiol. 2010. 83:e90–e94.
6. Guitart J. Subcutaneous lymphoma and related conditions. Dermatol Ther. 2010. 23:350–355.
7. Chiou HJ, Chou YH, Chiou SY, Chen WM, Chen W, Wang HK, et al. High-resolution ultrasonography of primary peripheral soft tissue lymphoma. J Ultrasound Med. 2005. 24:77–86.
8. Kang BS, Choi SH, Cha HJ, Jung YK, Lee JH, Jeong AK, et al. Subcutaneous panniculitis-like T-cell lymphoma: US and CT findings in three patients. Skeletal Radiol. 2007. 36:Suppl 1. S67–S71.
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