Maxillofac Plast Reconstr Surg.  2014 Mar;36(2):57-61.

Reconstruction of Defect after Treatment of Bisphosphonate-related Osteonecrois of the Jaw with Staged Iliac Bone Graft

• Ahn KJ
• Kim YK
• Yun PY

Abstract

Bisphosphonate is used widely for osteoporosis treatment, but a rising concern is the risk of osteonecrosis after long-term bisphosphonate use. Such cases are increasing, suggesting a need for research to prevent and treat bisphosphonate-related osteonecrosis of jaws. A 63-year-old female took bisphosphonate (Fosamax(R)) for four years for treatment of osteoporosis and stopped medication two months ago because of unhealed wound. She was treated with marginal mandibulectomy maintaining the inferior border, and a metal plate was placed to prevent mandible fracture. Four months after the mandibulectomy, mandible reconstruction surgery using iliac bone and allograft was done. Six months after reconstruction, implant placement and treatment with an overdenture was done without complications. This study presents a case with a successful result.

Keyword

Bisphosphonate-related osteonecrosis of jaws; Osteonecrosis; Implant; Overdenture

MeSH Terms

Allografts
Denture, Overlay
Female
Humans
Jaw*
Mandible
Middle Aged
Osteonecrosis
Osteoporosis
Transplants*
Wounds and Injuries