Obstet Gynecol Sci.  2014 May;57(3):240-243. 10.5468/ogs.2014.57.3.240.

Metastatic malignant melanoma with peritoneal seeding in a young woman: A case report

• Lee ES
• Ahn JH
• Lee TS
• Jeon HW

• KMID: 1704433
• DOI: http://doi.org/10.5468/ogs.2014.57.3.240

Abstract

Malignant melanomas of the uterus, either primary or metastatic, are extremely rare. They can be mistaken as other tumors, such as uterine sarcomas during diagnosis. We describe here the first case of a metastatic melanoma of the uterus with peritoneal seeding in a young woman. It was first diagnosed as a uterine sarcoma from a frozen-section biopsy.

Keyword

Melanoma; Neoplasm metastasis; Peritoneal seeding

MeSH Terms

Biopsy
Diagnosis
Female
Humans
Melanoma*
Neoplasm Metastasis
Sarcoma
Uterus

Figure

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  Fig. 1 (A) Enhanced computed tomography scan shows uterine mass (arrow). (B) Ascites, heterogenously enhanced peritoneal seeding and retroperitoneal seeding masses were seen. Lymph node enlargement was not shown.

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  Fig. 2 (A) Microscopic findings of the tumor. Tumor cells show infiltrative growth through myometrium (H&E, ×100). (B) There are focal areas with melanin pigment deposition by the tumor cells (H&E, ×200). Immunohistochemical staining demonstrates that the tumor cells are positive for S-100 (C) (×200) and also positive for HMB-45 (D) (×200).

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