J Korean Neurosurg Soc.  1992 Jul;21(7):760-766.

The Analysis of Intraventricular Hemorrhage Treated with Simple EVD or Infusion of Urokinase

• Shin JH
• Choi CS
• Ju MB

Abstract

Among all of the spontaneous TCH(intracerebral hemorrhage), the presence of IVH(intraventricular hemorrhage) is showing higher mortality and morbidity. Since the introduction of EVD(extraventricular drainage) and direct intraventricular infusion of Urokinase as a effective therapeutic methods of IVH, it's mortality and morbidity has been decreased. But, in cases of hemorrhage extended into all ventricular chambers showes poor prognosis even the EVD and infusion of Urokinase. Authors analyzed 40 cases of IVH treated with simple EVD or direct intraven-tricular infusion of Urokinase. The results were as follows: 1) The most common age groups of IVH patients were 5th and 6th decades and 22 patients were male, 18 patients were female. 2) All 15 cases of Urokinase treated group revealted over the 7 point of Graeb score. 3) On admission, Glasgow coma scale scores were under the 8 at the 11 cases(73%) of Urokinase treated group and 18 cases(72%) of simple EVD group. 4) Time of cleared ventricles showed fast at the Urokinase treated group than simple EVD group. 5) Incidence of complications were similar on both groups. 6) Prognosis revealed lower morbidity and mortality at the Urokinase treated group than simple EVD group. 7) In cases of high Graeb score and low Glasgow coma scale on admission showed poor prognosis in both groups.

Keyword

IVH; EVD; Urokinase; Graeb score

MeSH Terms

Female
Glasgow Coma Scale
Hemorrhage*
Humans
Incidence
Infusions, Intraventricular
Male
Mortality
Prognosis
Urokinase-Type Plasminogen Activator*
Urokinase-Type Plasminogen Activator