J Korean Neurosurg Soc.  1994 May;23(5):571-579.

Clinical Analysis of the Effect of the Continuous External Ventricular Drainage with Urokinase Irrigation for the Treatment of Intraventricular Hemorrhage

• Koh HS
• Song SH
• Kim SH
• Kim KT
• Kim Y

Abstract

The mortality and morbidity of the intraventricular hemorrhage(IVH) has been decreased since the introduction of external ventricular drainage(EVD) and direct intraventricular infusion of urokinase as an effective therapeutic method. In 1989, we already reported a series of 54 cases of IVH treated with simple EVD or EVD with urokinase irrigation in a few cases. Authors analyzed again a series of 50 cases of IVH treated by EVD with direct intraventricular urokinase irrigation after the pervious report. The mortality rate was 55.5% in former occasion, however 18% in this study and the complications were considerably low. We experienced again that the EVD with urokinase irrigation is an effective method and convenient, simple technique in the management of IVH even though there is no ICP monitoring. So we prefer EVD with urokinase irrigation therapy in managing the IVH even if the patient is moribund state.

Keyword

IVH; EVD; Urokinase irrigation; Effective method

MeSH Terms

Drainage*
Hemorrhage*
Humans
Infusions, Intraventricular
Mortality
Urokinase-Type Plasminogen Activator*
Urokinase-Type Plasminogen Activator