Korean J Dermatol.  1981 Jun;19(3):307-311.

A Case of Granuloma Annulare

Abstract

Granuloma, annulare is a chronic dermatosis characterized by skin colored, firm intradermal papules or subutaneous nodules, which may be discrete or arranged in an annular configuration. Histologically the dermis shows well define8 areas of necrobiosis of collagen tissue surrounded. by palisading histiocytes and lymphocytes. There may be lobules of epithelioid cells ani multinucleated giant ce.1s surrounding the necrobiotic areas. Many factors have been implicated in the genesis of this reaction. Recent studies have indicated that delayed hypersensitivity reactions rnay be involved in the pathogenesis of granuloma annulare. We present a typical granulorna annulare on a 16 year-old boy who had flesh colored, hyperkeratotic small nodules arranged in ring fashion on the dorsum of hands and right ear auricle.


MeSH Terms

Adolescent
Collagen
Dermis
Ear Auricle
Epithelioid Cells
Granuloma Annulare*
Granuloma*
Hand
Histiocytes
Humans
Hypersensitivity, Delayed
Lymphocytes
Male
Necrobiotic Disorders
Skin
Skin Diseases
Collagen
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