Korean J Dermatol.  1980 Aug;18(4):361-365.

Eoxinophilic FAsciitis: Report of a case

• Lee JB
• Kim SC
• Kim YK

Abstract

Eosinophilic fasciitis is a syndrome which is characterized by scleroderma-like skin involvement, eosinophilia and hypergammaglobulinemia without significant systemic changes. The primary pathological alterations are thickening and inflammation of the deep fascia. The majority of the cases that have been reportecd respond to systemic corticosteroids. We describe a 19-year-old male patient with eosinophilic fasciitis. On physical examination, he showed tender, edematous, indurated and tight skin in the back and both lower legs, and the laboratory findings showed eosinophilia and mild hypergammaglobulinemia. He also had Raynaud phenomenon, mild dyspnea, abdominal pain, pulmonary function abnormalities and roentgenographic evidence of pulmonary fibrosis. Result of a biopsy showed sclerosis of dermia and intense infiltrations of eosinophils, lymphocytes and histiocytes and fibroais of panniculus and fascia. Treatment with systemic corticosteroids showed complete resolution of the skin lesions, but after withdrawal new scleroderma-like skin lesions developed in the dorsum of feet.

MeSH Terms

Abdominal Pain
Adrenal Cortex Hormones
Biopsy
Dyspnea
Eosinophilia
Eosinophils
Fascia
Fasciitis*
Foot
Histiocytes
Humans
Hypergammaglobulinemia
Inflammation
Leg
Lymphocytes
Male
Physical Examination
Pulmonary Fibrosis
Raynaud Disease
Sclerosis
Skin
Young Adult
Adrenal Cortex Hormones