Korean Circ J.  1987 Dec;17(4):709-717. 10.4070/kcj.1987.17.4.709.

Radionuclide Assessment of Cardiac Performance in Dilated Cardiomyopathy

• Oh KY
• Roe IH
• Ahn MJ
• Kim KS
• Kim JH
• Lim HK
• Lee BH
• Lee CK
• Cho SS

• KMID: 1668912
• DOI: http://doi.org/10.4070/kcj.1987.17.4.709

Abstract

It has been well known that dilated cardiomyopathy (D-CMP) has characterized by systolic dysfunction of left ventricle (LV). But there are few studies about LV diastolic and right ventricular (RV) dysfunction in D-CMP. The purpose of this study is to assess the LV and RV systolic function as well as diastolic function in D-CMP. The purpose of this tudy is to assess the LV and RV systolic function as well as diastolic function in D-CMP. The gated blood pool scan (GBPS) was undertaken in 14 patients with D-CMP and 14 normal controls. The results are as follows : 1) Compared to normal controls, the global and regional ejection fraction of LV were significantly reduced (P<0.001) in D-CMP. But, there was no significant difference in LV ejection time between the two groups. 2) Peak filling rate and peak filling time were significantly reduced (P<0.001, P<0.05) in D-CMP 3) Global ejection fraction of RV was also significantly reduced in D-CMP compared to normal controls (P<0.001) But there was no significant difference in ejection rate of right ventricle between the two groups. 4) There was close correlation (R=0.802) between ejection fraction and filling rate of LV : filling rate was also reduced as ejection fraction decreased. And LV filling rate was also reduced with reduction of ejection rate. It is concluded that D-CMP shows diastolic impairment as well as systolic pumping failure and this systolic dysfunction is accounted for the diastolic impairment in D-CMP. And D-CMP shows also right ventricular dysfunction in almost all cases, as well as left ventricular dysfunction.

MeSH Terms

Cardiomyopathy, Dilated*
Heart Ventricles
Humans
Ventricular Dysfunction, Left
Ventricular Dysfunction, Right