J Korean Pediatr Soc.  1980 Apr;23(4):301-308.

Clinical Study of Mucocutaneous Lymph Node Syndrome-8 Cases

• Yoon KY
• Lee WG
• Lee KS

Abstract

We observed clinically 8 cases of MCLS who were admitted to the Department of Pediatrics, Hanyang University Hospital from July, 1977 to August, 1979 and following results were obtained. 1. This syndrome developed in mainly under 2 years old of age with preponderence and in mainly summer season.2. Clinical manifestation of MCLS are: 1) fever lasting from one two weeks. 2) conjunctival injection. 3) changes in the mouth consisting of erythema of the mucosa, strawberry tongue? and dry reddened and fissuring lips. 4) indurative edema of hands and feet with erythema on palms and soles, followed by desquamation of the finger tips during convalescent stage. 5) erythematous rash, mainly in trunk. 6) unilateral cervical lymphadenopathy. 3. Lab. Findings are mild anemia, leukocytosis, increased ESR, positive CRP, increased 2-globulin, marked thrombocytosis during recovery stage, proteinuria, and pyuria. 4. Fever and other symptoms of MCLS were subsided in much shorter period(4-5days) in high dose of aspirin symptoms of aspirin group(150-185mg/kg/day) than in usual dose of aspirin group(7-8days). And so high dose aspirin therapy seems to be effective in the treatment of MCLS and definitely shortened the clinical course during acute stage. 5. In spite of high dose aspirin theray, no complication was noted and completely recovered in all cases without any complications.

MeSH Terms

Anemia
Aspirin
Child, Preschool
Edema
Erythema
Exanthema
Fever
Fingers
Foot
Fragaria
Hand
Humans
Leukocytosis
Lip
Lymph Nodes*
Lymphatic Diseases
Mouth
Mucous Membrane
Pediatrics
Proteinuria
Pyuria
Thrombocytosis
Tongue
Aspirin