Korean J Med Mycol.
1996 Dec;1(1):11-23.
Recent Developments in Diagnosis and Treatment of Invasive Fungal Infections in Patients with Neoplastic Diseases
- Affiliations
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- 1Infectious Disease Section, Pediatric Branch, Division of Cancer Treatment National Cancer Institute, Bethesda, Maryland, 20892, USA.
Abstract
- Patients with neoplastic diseases are predisposed to develop invasive fungal infections as the result of impairment of host defense, due principally to pharmacological immuno-suppression as the resulting from intensive cytotoxic chemotherapy, ablative radiation therapy, and corticosteroids. Candida spp., Aspergillus spp., and emerging opportunistic fungal pathogens comprise the principal etiological agents of opportunistic mycoses in cancer patients. This paper will briefly review the recent progress in management of invasive fungal infections and the current problems of invasive mycosis, which currently confront patients with neoplastic diseases.