Korean J Dermatol.
1975 Mar;13(1):5-7.
Treatment of Hyperpigmented Disease with 4-Isopropylcatechol
Abstract
- Disfiguring hyperpigmentation of the exposed areas may have impartant and lasting effects on the emotional well-being of the patient. And many attempts to treat areas of hyperpigmentation have been earried out, but all of them are not very successful. Recently 4-isopropylcatechol has been known to inhibit melanin pigmentation with a selective action on melanocytes either destroying or inactivating the melanocytes experimentally. There is no report on its clinical trial till now. In this study, 1% 4-isopropylcatechol cream was topieally applied to the hyperpigmented lesions of 29 patieots of melasma, freckle, and cafe-au-lait spot. The bleaching effect on meiasmas was very satisfactory in all patients but coantact dermatltis in 3 patients and reticular hyperpigmentation with areas of depigmented spots in one patient were developed as the side effects of the drug. Freckle and cafe-au-Iait spots were not bleached.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Animal Experiments of Cutaneous Depigmentation by 4-Isoprophlcatechol and Hydroquinone
- Electron Microscopic Study in Tinea Versicolor: Structural Changes of Melanosomes Accompanying the Hyperpigmented and Hypopigmented Lesions
- Two cases of dyschromatosis universalis
- A Case of Pigmented Bowen's Disease in Perianal Area
- A Case of Becker's Nevus Associated with Ipsilateral Breast Hypoplasia
