Korean J Dermatol.  1974 Jun;12(2):21-24.

Clinical Effects of Combined Treatment of Prednisolone and Psoralen on Vitiligo

• Park YJ
• Lee SB
• Byun DG

Abstract

Although the psoralen therapy has been used extensively on vitligo since the : introduction by El-Mofty on 1948, the result has not been satisfactory. Recent investigations showed that the autoimmune mechanism might be the causative factor to the development of vitiligo, and the use of steroid might be expected to be beneficial in the treatment of this disorder. Authors tried the combined treatment of prednisolone and psoralen on vitiligo and the results obtained are as follows; 1. Repigmentations began to develop from injected area of prednisolone as well as frorn hair follicles and peripheral area of the lesions. 2. More satisiactory responses were obtained on the widespread and symmetrical lesions of shorter duration than on the lesions of localized and long duration.

MeSH Terms

Ficusin*
Hair Follicle
Prednisolone*
Vitiligo*
Ficusin
Prednisolone