Korean J Dermatol.  1973 Oct;11(2):115-117.

Solitary Trichopeithelioma Treated by 5-Fluorouracil Ointment Application

• Park YK
• Cho KY
• Woo TH

Abstract

Trichoepithelioma, a tumor of the hair follicle, is usually seen as multiple lesions, but occasionally appears as a single tumor. Multiple trichoepithelioma is a dominant hereditary skin conditions whereas solitary trichoepithelioma is not hereditary and is growing tumor, usually seen in adults. A case of 56 year old housewife with solitary trichoepithelioma was reported. The skin lesion appeased as a firm, skin colored papule and the size was 0.5cm in diameter on right side of nose. Shaving biopsy was done and showed a high degree of differentiation toward hair structure and horn cyst that the keratinization is abrupt and complete. The methood of treatment is a surgical excision and electrodesiccation but remain a scar due to surgical trauma. And so, we used a 5-fluorouracil ointment instead of surgical excision and electrodesiccation, The skin lesion on nose was cured completely as a result of 5-FU ointment application without any scar formation cosmetically.

MeSH Terms

Adult
Animals
Biopsy
Cicatrix
Fluorouracil*
Hair
Hair Follicle
Horns
Humans
Middle Aged
Nose
Skin
Fluorouracil