J Korean Neurol Assoc.  1996 Dec;14(4):1030-1034.

Cramp Fasciculation Syndrome

Affiliations
  • 1Department of Neurology, Yongdong Severance Hospital, Yonsei University College of Medicine.

Abstract

Cramp-fasciculation syndrome can be characterized by acute onset of action induced muscle cramps without weakness or muscle atrophy. The neurological examination is normal except for fasciculation or myokymia. Electromyography (BMG) shows fasciculation and muscle biopsy may show neurogenic abnormalities. We describe a 65 years old woman who had muscle cramps and fasciculations in the hands and bilateral feet for 2 months. Laboratory studies including CBC, erythrocyte sedimentation rate, serum electrolytes, blood chemistries, creatinekinase, serum magnesium, serum ionized calcium, thyroid function tests, parathyrold function tests, urinalysis were all normal. Motor and sensory nerve conduction studies were normal. EMG study showed fasciculation in the right abductor pollicis brevis muscle and the bilateral anterior tibialis muscles There were no showers of electrical potentials following the M-wave after repetitive median, ulnar, and peroneal nerve stimulations at the frequency of 1, 2, and 5-Hz. She improved dramatically after vitamin E treatment.


MeSH Terms

Aged
Biopsy
Blood Sedimentation
Calcium
Electrolytes
Electromyography
Fasciculation
Female
Foot
Hand
Humans
Magnesium
Muscle Cramp*
Muscles
Muscular Atrophy
Myokymia
Neural Conduction
Neurologic Examination
Neuromuscular Diseases*
Peroneal Nerve
Thyroid Function Tests
Urinalysis
Vitamin E
Vitamins
Calcium
Electrolytes
Magnesium
Vitamin E
Vitamins
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