J Korean Soc Ther Radiol.  1987 Jun;5(1):31-36.

Effect of Microwave Hyperthermia on Radiotherapy of Human Mailignant Tumors: An Analysis of Clinicl Response of 42 Patients

• Yoon SC
• Oho YK
• Gil HJ
• Chung SM
• Shinn KS
• Bahk YW

Abstract

Radiobiological and clinical evidences indicate that hyperthermia combined with ionizing radiation produces a significant improvement in therapeutic effect of cancer. In general, malignant cells are more sensitive to heat than normal cells in the heat range of 41~45degree C. We report the experiences obtained from 42 patients with advanced malignant neoplasms managed with 2,450 MHz microwave-induced local hyperthermia and ionizing radiation at the Department of Radiology, Kangnam St. Mary's Hospital, Catholic University Medical College. A clinical analysis of 42 thermoirradiated patients showed result of 11(26%), 15(36%), 11(26%) and 5(12%) patients with complete response (CR), partial response (PR), minor response (MR) and no response (NR), respectively. Histologically, there were 17 (40.2%) squamous cell carcinomas, 12(28.6%) adenocarcinomas and 6 (14.3%) miscellaneous cancers. Eleven patients with CR consisted of five squamous cell carcinomas, five adenocarcinomas, and one chloroma. Among 15 patients with PR were five squamous cell carcinomas, five adenocarcinomas, three unknown primary tumors, and one poorly differentiated, and miscellaneous tumor each.

Keyword

Microwave; Hyperthermia; Radiotherapy Malignant tumor; Clinical response

MeSH Terms

Adenocarcinoma
Carcinoma, Squamous Cell
Fever*
Hot Temperature
Humans*
Hyperthermia, Induced
Microwaves*
Neoplasms, Unknown Primary
Radiation, Ionizing
Radiotherapy*
Sarcoma, Myeloid