J Korean Soc Ther Radiol.
1985 Mar;3(1):9-12.
Radiosensitivity and Dose-urvival Characteristics of Crypt Cells of Mouse Jejunum
- Affiliations
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- 1Department of Radiology, College of Medicine, Soonchunhyang University, Korea.
- 2Department of Therapeutic Radiology, College of Medicine, Seoul University, Korea.
Abstract
- To determine the radiosensitivity and dose-urvival characteristics of jejunal crypt cells, experimental study was done using total 40 mice. Single irradiation of 1,000rad to 1,600rad was delivered to whole bodies of mice, using a cesium 137 animal irradiator. The number of regenerating crypts per jejunal circumference was counted, by using a jejunal crypt cell assay technique, and dose response curve was measured. The average number of jejunal crypt per circumference in control group was 140+/-10. Mean lethal dose(D0) of mouse jejunal crypt cell was 135rad.
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