Korean J Med.
2004 Apr;66(4):404-407.
A case of Guillain-Barre syndrome with syndrome of inappropriate antidiuretic hormone secretion (SIADH)
- Affiliations
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- 1Department of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea. kimjhmd@daum.net
- 2Department of Neurology, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea.
Abstract
- SIADH was first described by Schwartz and colleagues in 2 patients with bronchogenic lung carcinoma as early as 1957. The main features of the syndrome consist of hyponatremia and hypotonicity, absence of fluid volume depletion, inappropriate urinary osmolality, increased urinary sodium excretion while on normal salt and water intake, and absence of thyroid, adrenal, pituitary or renal dysfunction. The Guillain-Barre Syndrome (GBS) is an acute inflammatory demyelinating polyradiculoneuropathy of unknown etiology. It occurs frequently one to three weeks after a banal antecedent respiratory or gastrointestinal infection. SIADH is associated with various condition such as malignant tumors, infection, central nervous system disorders, and different pharmacological agents. SIADH is observed in up to 26% of patients with Guillain-Barre Syndrome (GBS). We report a case of GBS with SIADH.
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