Korean J Dermatol.
2002 Feb;40(2):191-194.
A Case of HMB-45 Negative Hypopigmented Cellular Blue Nevus
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- 1Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Abstract
- Blue nevus is a benign pigmented lesion of dermal melanocytes with a number of histologic and clinical variants. We report a variant of cellular blue nevus that is minimally pigmented. Immunohistochemistry showed the case to be strongly positive with S-100 protein, but negative with Ki-67 and HMB-45 antibody. There is a potential for hypopigmented cellular blue nevus to be confused with other benign nevus, such as intradermal nevus, Spitz nevus, and deep penetrating nevus and malignant melanoma.
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