Korean J Dermatol.  2006 Mar;44(3):338-340.

A Case of Radiation Recall Dermatitis which Developed in a Patient with Kaposi Sarcoma

• Lee SE
• Lew W

Abstract

Radiation recall dermatitis is a rare skin reaction, occurring subsequent to drug administration, and has all the clinical signs of inflammation, which develop in a previously irradiated area, days to years after exposure to ionizing radiation. A 41-year-old woman was diagnosed with Kaposi sarcoma. The patient was treated by radiotherapy, followed by a 1st chemotherapy session with doxorubicin and ifosfamide, 20 days after the radiotherapy. However, the patient developed erythema of the skin, accompanied by pruritus and pain in the previously irradiated area, 3 to 4 days after the chemotherapy. The erythema resolved almost completely after systemic and topical steroid therapy. The patient received a 2nd chemotherapy session with the same regimen, but there was no recurrence of radiation recall dermatitis. We report a case of an uncommon skin reaction after chemotherapy in a patient with kaposi sarcoma, which was identified as radiation recall dermatitis.

Keyword

Doxorubicin; Kaposi sarcoma; Radiation recall dermatitis

MeSH Terms

Adult
Doxorubicin
Drug Therapy
Erythema
Female
Humans
Ifosfamide
Inflammation
Pruritus
Radiation, Ionizing
Radiodermatitis*
Radiotherapy
Recurrence
Sarcoma, Kaposi*
Skin
Doxorubicin
Ifosfamide