Korean J Hematol.  2004 Sep;39(3):182-185.

A Case of Coincident Multiple Myeloma and Nasal NK/T-Cell Lymphoma

• Lee WS

Abstract

The coexistence of non-Hodgkin's lymphoma and multiple myeloma is very rare and the coexistence of nasal NK/T-cell lymphoma and multiple myeloma has never been reported in the literature. Recently, a 63-year-old woman was presented with small amount of hematemesis. Bone marrow showed increased immature plasma cell (72.5%). Serum protein electrophoresis showed monoclonal gammopathy (6.5g/dL). Serum immunoelectrophoresis showed IgG and kappa type monoclonality. Microscopic examination of left nasopharynx and inferior turbinate revealed nasal NK/T-cell lymphoma. Six cycles of CHOP (cyclophosphamide, daunomycin, vincristine, prednisone) chemotherapy induced the complete remission of both tumors, but died of cerebral involvement of NK/T-cell lymphoma in 12 months after the diagnosis.

Keyword

Coexistence; Multiple Myeloma; Nasal NK/T-cell lymphoma; Non-Hodgkin's Lymphoma

MeSH Terms

Bone Marrow
Daunorubicin
Diagnosis
Drug Therapy
Electrophoresis
Female
Hematemesis
Humans
Immunoelectrophoresis
Immunoglobulin G
Lymphoma*
Lymphoma, Non-Hodgkin
Middle Aged
Multiple Myeloma*
Nasopharynx
Paraproteinemias
Plasma Cells
Turbinates
Vincristine
Daunorubicin
Immunoglobulin G
Vincristine