J Korean Neurol Assoc.
2006 Dec;24(6):596-600.
Four Cases of Probable Creutzfeldt-Jacob Disease with High Signals in Cerebral Cortex on Diffusion Weighted MR Imaging
- Affiliations
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- 1Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea. ytkwak@drkwak.com
- 2Department of Neurology, Ajou University College of Medicine, Suwon, Korea.
- 3Department of Neurology, Pochon CHA University College of Medicine, Seongnam, Korea.
- 4Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- A high signal in the cerebral cortex and/or basal ganglia on a diffusion-weighted MRI (DWI) has been described as a good diagnostic marker for sporadic Creutzfeldt-Jakob disease (sCJD). We report four cases of sCJD with atypical clinical presentations and ribbon-like areas of high signals in the cerebral cortex on DWI. DWI patterns of asymmetric cortical high signals in the cerebral cortex may offer the means for diagnosis of sCJD early in the course of the illness even when the clinical presentations are atypical.
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