Korean J Pediatr Gastroenterol Nutr.  2003 Mar;6(1):59-67.

A Case of Congenital Cytomegalovirus Colitis with Colonic Stricture

Affiliations
  • 1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. jkseo@snu.ac.kr
  • 2Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
  • 4Department of Pediatric Surgery, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Congenital cytomegalovirus (CMV) infections are usually asymptomatic in newborns or may present with rash, hepatosplenomegaly, jaundice, pneumonia, and the development of central nervous system sequelae. Gastrointestinal involvement of congenital CMV infection complicating stricture has been rarely reported, especially in children. We report a case of a 2-month-old body who presented with bloody stool since 3 days of age. Hemotochezia was attributable to CMV colitis with colonic stricture, which was confirmed by histopathology, serologic studies and virus culture. Clinical status of the patient improved with intravenous administration of ganciclovir.

Keyword

Congenital infection; Cytomegalovirus; Colitis; Stricture

MeSH Terms

Administration, Intravenous
Central Nervous System
Child
Colitis*
Colon*
Constriction, Pathologic*
Cytomegalovirus*
Exanthema
Ganciclovir
Humans
Infant
Infant, Newborn
Jaundice
Pneumonia
Ganciclovir
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