Korean J Pathol.
2005 Jun;39(3):197-199.
Aspergillous Hypophysitis: A Case Report
- Affiliations
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- 1Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea. kkmkys@catholic.ac.kr
Abstract
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Aspergillous hypophysitis is an unusual cause of sella turcica enlargement, and this malady has a clinical presentation as a pituitary tumor, and especially as a pituitary adenoma. We report here on a case of aspergillous hypophysitis that developed in a 37-year-old healthy woman. She first experienced a blurred vision with amenorrhea and galactorrhea. Three months later, the CT scan revealed an intrasellar mass. The patient underwent a transsphenoidal exploration of the sella turcica for a presumed pituitary tumor. Histologically, the pituitary displayed necrotizing granuloma with the acutely branching fungal hyphae of Aspergillus.