Korean J Pathol.  2005 Jun;39(3):197-199.

Aspergillous Hypophysitis: A Case Report

Affiliations
  • 1Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea. kkmkys@catholic.ac.kr

Abstract

Aspergillous hypophysitis is an unusual cause of sella turcica enlargement, and this malady has a clinical presentation as a pituitary tumor, and especially as a pituitary adenoma. We report here on a case of aspergillous hypophysitis that developed in a 37-year-old healthy woman. She first experienced a blurred vision with amenorrhea and galactorrhea. Three months later, the CT scan revealed an intrasellar mass. The patient underwent a transsphenoidal exploration of the sella turcica for a presumed pituitary tumor. Histologically, the pituitary displayed necrotizing granuloma with the acutely branching fungal hyphae of Aspergillus.

Keyword

Aspergillosis; Pituitary gland

MeSH Terms

Adult
Amenorrhea
Aspergillosis
Aspergillus
Female
Galactorrhea
Granuloma
Humans
Hyphae
Pituitary Gland
Pituitary Neoplasms
Pregnancy
Sella Turcica
Tomography, X-Ray Computed
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