Korean J Dermatol.
2001 Mar;39(3):379-381.
A Case of Spontanous Bullae at Recipient Site after Epidermal Graft for the Treatment of Vitiligo
- Affiliations
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- 1Department of Dermatology, Chon-buk University Medical School, Chonju, South Korea. dermt@moak.chonbuk.ac.kr
Abstract
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Vesicles and bullae are the primary lesions in many diseases. The histologic classification of bullous disorders is based on the level in the skin on which that cleavage developed. We report a 44-year-old man with vitiligo at dorsum of hand who has experienced spontanous bullae at recipient site after epidermal graft for the treatment of vitiligo. Histopathologic examination revealed a subepidermal bullae and moderate lymphocytes and eosinophil infiltration in the dermis. Direct immunofluorescence test was negative. There was a change of CD4/CD8 ratio in immunohistochemical staining for CD4 and CD8 monoclonal antibody. There were no clinical signs of infection and drug eruption, and friction did not seem to have been a contributing factor.