J Lab Med Qual Assur.  2005 Jun;27(1):37-57.

Annual Report on External Quality Assessment in Immunoserology in Korea (2004)

• Cha YJ
• Kwon SY
• Kum DG
• Kim SW
• Kim TY
• Kim JR
• Kim HS
• Park MH
• Park SH
• Park AJ
• Son HC
• Yang JS
• Lee KS
• Chae SL

Abstract

The followings are the results for external quality assessment (EQA) in immunoserology for 2004: 1. Evaluation of EQA was done in 2 trials in May and November, about 99% of laboratories participating average 8.4 items. EQA for anti-HBc test was newly started in 2004. 2. Commercial control, MASR Immunology Control from Medical Analysis Systems (Camarillo, CA, USA) was used to assure the quality of quantitative results of C-reactive protein (CRP), rheumatoid factor (RF) and anti-streptolysin O (ASO) tests in 2004. All the specimens for Immunoserology in EQA were delivered refrigerated for the first time, being received within 48 hours after sending. 3. EQA for detection of HBsAg mutants was tried for the first time, using the recombinant HBsAg mutant (Gly/Arg 145) kindly provided by Abbott Laboratories, USA. 4. The laboratories using immunochromatography assay (ICA) were increased, however, many laboratories using ICA reported falsely negative for the positive specimens. The sensitivity of ICA test kits as well as various factors influencing the ICA results should be evaluated. 5. Standardization of methods including calibrators for quantitative results should be required for the harmonization of results.

Keyword

Immunoserology; External quality assessment; HBsAg; HBsAg mutant; Anti-HBs; Anti-HCV; Anti-HIV; CRP; RF; ASO; Widal; STS; ICA; CIA; EIA; MEIA; nephelometry; TIA

MeSH Terms

Allergy and Immunology
C-Reactive Protein
Hepatitis B Surface Antigens
Immunochromatography
Korea*
Nephelometry and Turbidimetry
Rheumatoid Factor
C-Reactive Protein
Hepatitis B Surface Antigens
Rheumatoid Factor