J Breast Cancer.  2005 Jun;8(2):69-73. 10.4048/jbc.2005.8.2.69.

Combined Multimodality Treatment including Surgery

• Bang MJ
• Bong JG
• Park JH
• Jeong MH
• Paik SM

• KMID: 1573954
• DOI: http://doi.org/10.4048/jbc.2005.8.2.69

Abstract

An ipsilateral supraclavicular lymph node recurrence of breast cancer after surgery has been considered a predecessor to distant metastases. There still is a debate as to whether breast carcinoma patients with the isolated supraclavicular lymph node recurrence should be considered to have disseminated disease or if aggressive treatment, with curative intent, is justified. We report two cases of an isolated ipsilateral supraclavicular lymph node recurrence following modified radical mastectomy, and multimodality treatments with modified radical neck dissection, systemic chemotherapy and involved field radiotherapy. These patients have lived without locoregional recurrence or distant metastases for 3 and 2 years, respectively. Conclusively, we recommend aggressive combined multimodality treatments, including surgery, such as modified radical neck dissection or complete excision of the involved lymph nodes, systemic chemotherapy, and involved field radiotherapy, in patients with isolated supraclavicular lymph node recurrence, but with no other evidence of distant metastases.

Keyword

Breast cancer; Supraclavicular lymph node; Recurrence; Multimodality treatments

MeSH Terms

Breast Neoplasms
Drug Therapy
Humans
Lymph Nodes
Mastectomy, Modified Radical
Neck Dissection
Neoplasm Metastasis
Radiotherapy
Recurrence