Korean J Med.  1998 Dec;55(6):1088-1092.

A Case of intracranial hemorrhage with polyradiculoneuropathy in Hypereosinophilic Syndrome

Affiliations
  • 1Department of internal medicine, No Won General Hospital, Seoul, Korea.

Abstract

Clinical criteria have been established for idiopathic hypereosinophilic syndrome (HES): persistent eosinophilia of 1500 eosinophils/mm3 for at least 6 months or death even within 6 months with signs and symptoms of HES; no evidence for parasitic, allergic, or other recognized causes of eosinophilia despite careful evaluation; and signs and symptoms of organ system involvement or dysfunction, such as congestive heart failure, hepatosplenomegaly, central nerveous system disease. Because cerebral hemorrhage in HES has not been reported yet in Korea, we report a case of hypereosinophilic syndrome with peripheral blood eosinophilia, with biopsies of skin and duodenum showing diffuse eosinophilic infiltration, and multiple organ dysfunction in a 49 year old man died of cerebral hemorrhage three months after the occurrence of the disease.

Keyword

hypereosinophilic syndrome; intracranial hemorrhage

MeSH Terms

Biopsy
Cerebral Hemorrhage
Duodenum
Eosinophilia
Eosinophils
Heart Failure
Humans
Hypereosinophilic Syndrome*
Intracranial Hemorrhages*
Korea
Middle Aged
Polyradiculoneuropathy*
Skin
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