J Korean Soc Med Ultrasound.
1999 Sep;18(3):161-166.
Usefulness of High-Resolution Sonography in Early Diagnosis of Rabbit Clonorchiasis
- Affiliations
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- 1Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
- 2Department of Parasitology, Seoul National University College of Medicine, Korea.
Abstract
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PURPOSE: To determine the role of high-resolution sonography in the early diagnosis of experimentally induced clonorchiasis in rabbits.
MATERIALS and METHODS
We performed sonographic examination weekly in 22 lightly-infected rabbits (10 rabbits infected with 10 metacercariae, 6 rabbits infected with 20 metacercariae, and 6 rabbits infected with 40 metacer-cariae), and 10 heavily-infected rabbits (500 metacercariae). The sonographic criterion of diagnosis was dilatation of the intrahepatic ducts. We sacrificed lightly-infected rabbits and counted numbers of adult worms of Clonorchis sinensis 9 weeks after infection.
RESULTS
Sonographic abnormalities were found 3 weeks after infection in 2 lightly-infected rabbits and 5 heavily-infected rabbits. On sonography at 9 weeks after infection, we observed dilatation of the intrahepatic ducts in 11 (65%) of 17 lightly-infected rabbits and all of 10 heavily-infected rabbits.
CONCLUSION
High-resolution sonography is very useful in early diagnosis of rabbit clonorchiasis.
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