Korean J Infect Dis.
1997 Sep;29(5):447-451.
Two Cases of Salmonella typhi Liver Abscess after Transarterial- Chemoembolization
- Affiliations
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- 1Department of Internal Medicine, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.
- 2Department of Clinical Pathology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.
Abstract
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Hepatocellular carcinoma (HCC) is one of the most common malignancies in Korea. Transarterial chemoembolization (TACE) is an effective modality for treating HCC with a few complications. Liver abscess is most common infectious complication during post-TACE period. However, liver abscess caused by Salmonella typhi has never been reported. We experienced two cases of liver abscess following TACE, caused by S. typhi. Th clinical manifestations of S. typhi liver abscess are similar with other pyogenic liver abscesses. The CT scans showed liver abscesses mixed with necrotic materials after TACE, and the cultures of blood and abscess aspirates yielded S. typhi. The patients did not respond well only with the antibiotic treatment and was controlled after percutaneous drainage. A possible pathogenesis of these liver abscesses is considered as secondary infection in the necrotic liver tissues in biliary carrier of S. typhi.