- A Salmonella Typhi ghost induced by the E gene of phage φX174 stimulates dendritic cells and efficiently activates the adaptive immune response
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Won G, Eo SK, Park SY, Hur J, Lee JH
- KMID: 2417569
- J Vet Sci.
- 2018 Jul;19(4):536-542.
- doi: 10.4142/jvs.2018.19.4.536
Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive... -
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- Salicylic Acid Reduces OmpF Expression, Rendering Salmonella enterica Serovar Typhimurium More Resistant to Cephalosporin Antibiotics
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Choi KM, Kim MH, Cai H, Lee YJ, Hong Y, Ryu PY
- KMID: 2458580
- Chonnam Med J.
- 2018 Jan;54(1):17-23.
- doi: 10.4068/cmj.2018.54.1.17
Salmonella enterica serovar Typhimurium is one of the most important bacterial pathogens causing diarrhea. The resistance of S. typhimurium to antimicrobial agents, which has recently been isolated from patients, is... -
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- Prevalence and pathologic study of porcine salmonellosis in Jeju
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Yang HS, Kang SC, Kim AR, Jung BY, Kim JH
- KMID: 2401293
- Korean J Vet Res.
- 2017 Dec;57(4):235-243.
- doi: 10.14405/kjvr.2017.57.4.235
Salmonella (S.) Typhimurium is highly contagious, and its infection may rapidly spread within pig populations of herd. According to the survey (1,191 pigs) from 2003 to 2012, 155 pigs (13.0%)... -
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- Salmonella-Mediated Cancer Therapy: Roles and Potential
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Nguyen VH, Min JJ
- KMID: 2446892
- Nucl Med Mol Imaging.
- 2017 Jun;51(2):118-126.
- doi: 10.1007/s13139-016-0415-z
The use of bacteria for cancer therapy, which was proposed many years ago, was not recognized as a potential therapeutic strategy until recently. Technological advances and updated knowledge have enabled... -
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- Probiotic properties and adsorption of Enterococcus faecalis PSCT3-7 to vermiculite
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Kim JY, Awji EG, Park NH, Park JY, Kim JC, Lee SP, Suh JW, Park SC
- KMID: 2412593
- J Vet Sci.
- 2017 Mar;18(1):95-99.
- doi: 10.4142/jvs.2017.18.1.95
The probiotic properties of Enterococcus (E.) faecalis PSCT3-7, a new strain isolated from the intestines of pigs fed dietary fiber containing 50% sawdust, were investigated. E. faecalis PSCT3-7 tolerated a... -
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- Enhancement of Gastric Ulcer Healing and Angiogenesis by Hepatocyte Growth Factor Gene Mediated by Attenuated Salmonella in Rats
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Ha X, Peng J, Zhao H, Deng Z, Dong J, Fan H, Zhao Y, Li B, Feng Q, Yang Z
- KMID: 2364161
- J Korean Med Sci.
- 2017 Feb;32(2):186-194.
- doi: 10.3346/jkms.2017.32.2.186
The present study developed an oral hepatocyte growth factor (HGF) gene therapy strategy for gastric ulcers treatment. An attenuated Salmonella typhimurium that stably expressed high HGF (named as TPH) was... -
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- Targeted Cancer Therapy Using Engineered Salmonella typhimurium
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Zheng JH, Min JJ
- KMID: 2432267
- Chonnam Med J.
- 2016 Sep;52(3):173-184.
- doi: 10.4068/cmj.2016.52.3.173
Obligate or facultative anaerobic bacteria such as Bifidobacterium, Clostridium, Salmonella, or Escherichia coli specifically colonize and proliferate inside tumor tissues and inhibit tumor growth. Among them, attenuated Salmonella typhimurium (S.... -
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- Transcriptional Analysis of the iagB within Salmonella Pathogenicity Island 1 (SPI1)
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Lim S, Choi J, Kim D, Seo HS
- KMID: 2353847
- J Bacteriol Virol.
- 2016 Sep;46(3):128-134.
- doi: 10.4167/jbv.2016.46.3.128
HilA is a central regulator of Salmonella pathogenicity island 1 (SPI1), which is necessary for host invasion by Salmonella and induction of gastroenteritis. The iagB lies downstream of hilA and... -
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- Transcriptional Profiling of an Attenuated Salmonella Typhimurium ptsI Mutant Strain Under Low-oxygen Conditions using Microarray Analysis
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Lim S, Han A, Kim D, Seo HS
- KMID: 2068735
- J Bacteriol Virol.
- 2015 Sep;45(3):200-214.
- doi: 10.4167/jbv.2015.45.3.200
Salmonella causes a wide variety of diseases ranging from mild diarrhea to severe systemic infections, such as like typhoid fever, in multiple organisms, ranging from mice to humans. A lack... -
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- Targeting Orthotopic Glioma in Mice with Genetically Engineered Salmonella typhimurium
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Wen M, Jung S, Moon KS, Jiang SN, Li SY, Min JJ
- KMID: 2191077
- J Korean Neurosurg Soc.
- 2014 Mar;55(3):131-135.
- doi: 10.3340/jkns.2014.55.3.131
OBJECTIVE: With the growing interests of bacteria as a targeting vector for cancer treatment, diverse genetically engineered Salmonella has been reported to be capable of targeting primary or metastatic tumor... -
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- Evaluation of Immune Response for Vi-CRM(197) Conjugated Vaccine against Salmonella enterica serovar Typhi in Mice
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Kim K, Shim J, Park S, Park B, Cho Y, Hur B, Kang SA, Choi SK, Baik Y, Hahn TW
- KMID: 2135357
- J Bacteriol Virol.
- 2014 Mar;44(1):52-58.
- doi: 10.4167/jbv.2014.44.1.52
Typhoid fever, a serious systemic infection caused by Salmonella enterica serovar Typhi, breaks out in developing countries. However, existing vaccines only induce relatively low protective effects with humoral responses and... -
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- The Synergistic Effects of Antimicrobial Peptides on the Growth Inhibition of Salmonella Typhimurium through Imd Pathway in Drosophila Intestine
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Lim YJ, Jo YH, Kim HJ, Park JK
- KMID: 2168681
- J Bacteriol Virol.
- 2013 Jun;43(2):120-130.
- doi: 10.4167/jbv.2013.43.2.120
Some Bacillus species present in fermented foods are regarded as probiotics because of their ability to modulate the prevention of some intestinal infections and the modulation of the inflammatory immune... -
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- A Case of Renal and Liver Abscesses Caused by Nalidixic Acid-Resistant Salmonella typhi
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Lim SY, Kim HJ, Han JS, Kang DH, Lee JA, Lee SS, Kim MJ
- KMID: 2082473
- Korean J Med.
- 2013 Apr;84(4):608-612.
Prompt antibiotic treatment reduces the incidence of complications such as liver abscesses, pyelonephritis, and osteomyelitis in patients with typhoid fever. Renal or liver abscesses are especially rare in patients without... -
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- Changes of characterization of Salmonella Typhimurium isolate following sequential exposures to porcine neutrophil
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Lee HS, Kim A, Youn M, Lee JY, Lim SK, Kang HY, Yoo HS, Park JW, Wee SH, Jung SC
- KMID: 1991790
- Korean J Vet Res.
- 2013 Mar;53(1):29-35.
To develop a live vaccine candidate using an attenuated strain of Salmonella Typhimurium (ST), biochemical properties, plasmid profile, PFGE patterns and pathogenic analysis of the ST isolate were carried out... -
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- A Case of Salmonella Typhi Complicating Acute Appendicitis Proven by Gene STY0312 Polymerase Chain Reaction (PCR)
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Seo MJ, Jung YH, Min JW, Kim YJ, Lee JM, Yang H, Kim YS, Kim YS, Park CM, Yoo JH
- KMID: 1806930
- Infect Chemother.
- 2012 Dec;44(6):450-453.
- doi: 10.3947/ic.2012.44.6.450
Typhoid fever frequently manifests as gastrointestinal complications, such as ileitis or colitis, but appendicitis is quite rare. A 37-year-old man was admitted due to abdominal pain, fever and diarrhea. Two... -
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- Therapeutic effects of recombinant Salmonella typhimurium harboring CCL22 miRNA on atopic dermatitis-like skin in mice
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Yoon WS, Lee SS, Chae YS, Park YK
- KMID: 1097263
- Exp Mol Med.
- 2011 Feb;43(2):63-70.
- doi: 10.3858/emm.2011.43.2.008
Th-2-biased immune responses are known to play a key role in the pathogenesis of atopic dermatitis. In particular, the macrophage-derived chemokine CCL22 is directly implicated in Th-2-associated skin inflammatory reactions,... -
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- Further Evaluation of Multiplex PCR for Rapid Detection of Salmonella Typhi
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Lee DY, Min JE, Lee E, Kim SH, Oh HB, Park MS
- KMID: 1457384
- Infect Chemother.
- 2010 Aug;42(4):237-240.
- doi: 10.3947/ic.2010.42.4.237
Typhoid fever is a class I legally designated communicable disease in Korea; and if remains as an important public health problem in many developing countries. It takes at least 3-5... -
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- A multiplex real-time PCR for differential detection and quantification of Salmonella spp., Salmonella enterica serovar Typhimurium and Enteritidis in meats
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Lee SH, Jung BY, Rayamahji , Lee HS, Jeon WJ, Choi KS, Kweon CH, Yoo HS
- KMID: 1089345
- J Vet Sci.
- 2009 Mar;10(1):43-51.
- doi: 10.4142/jvs.2009.10.1.43
Salmonella (S.) Typhimurium and S. Enteritidis are the major causative agents of food-borne illnesses worldwide. Currently, a rapid detection system using multiplex real-time polymerase chain reaction (PCR) has been applied... -
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- Time Kill Studies of Antibiotics against a Nalidixic Acid Resistant Salmonella enterica serotype Typhi
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Kim DM, Yun NR, Chung JH, Ryu HH
- KMID: 2170235
- Infect Chemother.
- 2008 Aug;40(4):207-211.
- doi: 10.3947/ic.2008.40.4.207
BACKGROUND: We recently encountered a case of typhoid fever in a patient who visited us after travelling India. The patient received ciprofloxacin therapy, but developed typhoid pneumonia and typhoid hepatitis,... -
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- A case of typhoid fever with manifestations of acute hepatitis
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Hwang JW, Lee HM, Han DH, Oh JE, Ha JS, Cho DH, Shim SG
- KMID: 2256166
- Korean J Med.
- 2008 Jul;75(1):77-81.
Typhoid fever is a febrile illness with a variety of systemic manifestations; however, icteric typhoid hepatitis, mimicking the clinical features of acute hepatitis, is very uncommon. A 45-year-old man was... -
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