Korean J Oral Maxillofac Radiol.  2000 Jun;30(2):144-148.

Sjogren's syndrome combined with MALT lymphoma

Affiliations
  • 1Department of Oral and Maxillofacial Radiology, School of Dentistry, Dankook University, Korea. wjhan@anseo.dankook.ac.kr

Abstract

Sjogren's syndrome is a chronic inflammatory disease that predominantly affects salivary, lacrimal, and other exocrine glands. We report a case of Sjogren's syndrome combined with MALT(mucose associated lymphoid tissue) lymphoma which occured in the parotid gland. A 57-year-old female with the complaint of painful swelling and lymph node enlargement was referred to our department. Sialograms of both parotid glands showed globular collections of contrast material uniformly distributed throughout the parotid gland. Salivary scintigraphy showed decreased uptake of the parotid gland. CT scan showed larger, slightly more dense parotid gland than normal and honeycomb glandular appearance. Also, It showed discrete, slightly more enhanced round mass in the left parotid gland. Histopathological finding showed replacement of salivary gland parenchyma with dense small lymphocytic infiltration having the feature of epimyoepithelial islands. Kappa light chain restriction of interglandular plasma cell could be seen.

Keyword

Sjogren syndrome; lymphoma; parotid gland

MeSH Terms

Exocrine Glands
Female
Humans
Islands
Lymph Nodes
Lymphoma
Lymphoma, B-Cell, Marginal Zone*
Middle Aged
Parotid Gland
Plasma Cells
Radionuclide Imaging
Salivary Glands
Sjogren's Syndrome*
Tomography, X-Ray Computed
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