Korean J Gastrointest Endosc.  2000 Jan;20(1):53-57.

A Case of Hypertrophic Gastropathy and Early Gastric Cancer Associated with Pachydermoperiostosis

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Pachydermoperiostosis is a rare hereditary syndrome characterized by finger clubbing, periosteal new bone formation of tubular bones, and hypertrophic skin changes (pachydermia). This syndrome is known to be associated with a variety of diseases such as cranial suture defect, female escuchen, bone marrow failure and autonomic nervous system symptoms such as facial flushing and hyperhidrosis. There are just a few reports documenting gastric ulcer, hypertrophic gastropathy and Crohn's disease as associated diseases. A case is herein reported of pachydermoperiostosis accompanied by hypertrophic gastropathy and early gastric cancer.

Keyword

Pachydermoperiostosis; Hypertrophic gastropathy; Early gastric cancer

MeSH Terms

Autonomic Nervous System
Bone Marrow
Cranial Sutures
Crohn Disease
Female
Fingers
Flushing
Humans
Hyperhidrosis
Osteoarthropathy, Primary Hypertrophic*
Osteogenesis
Skin
Stomach Neoplasms*
Stomach Ulcer
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