Hanyang Med Rev.  2007 Aug;27(3):4-27.

Structural and Physio-chemical Properties of Helicobacter pylori

• Cho MJ

Abstract

In 1983 when Marshall and Warren first reported the gastric pathogen H. pylori, microbiologists and gastroenterologists would not have predicted that this bacterium would have been shown to be one of the most common bacterial infection in human and the ethiologic agent of the majority of gastrodoudenal disorders. Although there are many documents of the presence of a gastric pathogen in the stomach of human, few have paid attention to it due to difficulty in sampling and bias for asceptic conditions of gastric juice. Now H. pylori is recognized as an etiological pathogen of gastroduodenal disorders including chronic gastritis, peptic ulcer, and gastric cancers. H. pylori colonizes, restricted to gastric mucosa resulting in pathogenic events for inflammatory responses. Bacterial components of H. pylori could contribute to its adherence, adaptation, and colonization to/in gastric mucosa of human, of which understaning might provide insihgts for prevention, diagnosis, and treatment of H. pylori infection.

Keyword

Helicobacter pylori; Microbiological; Gastroduonenal diseases

MeSH Terms

Bacterial Infections
Bias (Epidemiology)
Colon
Diagnosis
Gastric Juice
Gastric Mucosa
Gastritis
Helicobacter pylori*
Helicobacter*
Humans
Peptic Ulcer
Stomach
Stomach Neoplasms