J Korean Endocr Soc.  2007 Apr;22(2):130-134. 10.3803/jkes.2007.22.2.130.

A Case of Kallmann's Syndrome Mildly Presenting as Secondary Amenorrhea

• Joo NR
• Park CY
• Moon HJ
• Kang JG
• Ihm SH
• Choi MG
• Yoo HJ
• Lee Y
• Oh KW
• Park SW

• KMID: 1523094
• DOI: http://doi.org/10.3803/jkes.2007.22.2.130

Abstract

Kallmann's syndrome is very rare congenital defect in GnRH (gonadotrophin releasing hormone) secretion involving both sexes. The mode of inheritance has not been fully understood. But, including X-linked inheritance, the ratio of incidence between male versus female is 5:1, and there is a few case reports of female Kallmann's syndrome in Korea, especially in internal medicine department. We report a case of 35 year-old female Kallmann's syndrome presenting secondary amenorrhea as a mild presentation.

Keyword

Female; Kallmann's syndrome; Secondary amenorrhea

MeSH Terms

Adult
Amenorrhea*
Congenital Abnormalities
Female
Genes, X-Linked
Gonadotropin-Releasing Hormone
Humans
Incidence
Internal Medicine
Kallmann Syndrome*
Korea
Male
Wills
Gonadotropin-Releasing Hormone

Figure

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  Fig. 1 Olfactory MRI - Coronal Section (A-T1, B-T2 image). Both olfactory bulbs are not visualized. Right side olfactory sulcus is not noted and left side olfactory sulcus (A, B- arrow) is also hypoplastic. There is no demonstrable other abnormality in subfrontal brain, and sino-nasal cavity.

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