J Lab Med Qual Assur.  2004 Dec;26(2):229-232.

Spuriously Increased Neutrophil Count on a Hematology Analyzer in Chronic Lymphocytic Leukemia: Report of Two Cases

Affiliations
  • 1Department of Laboratory Medicine, Hallym University College of Medicine, Anyang, Korea. kangheejung@hallym.or.kr

Abstract

We describe two cases of chronic lymphocytic leukemia (CLL) with spuriously increased neutrophil count by the Sysmex SE-9000 hematology analyzer. Each case showed an excess of small lymphocytic cells in blood film microscopy, and a large group of plots in the lymphocyte area was observed on the differential scattergram of the SE-9000. In the cases of CLL, there is a possibility of overestimation of neutrophil count by the SE-9000. Microscopic examination and review of differential scattergram of the SE-9000 are necessary in the cases with increased leukocyte count.

Keyword

Chronic lymphocytic leukemia; Hematoloty analyzer; Neutrophil count

MeSH Terms

Hematology*
Leukemia, Lymphocytic, Chronic, B-Cell*
Leukocyte Count
Lymphocytes
Microscopy
Neutrophils*
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