J Korean Assoc Maxillofac Plast Reconstr Surg.  2004 Sep;26(5):453-460.

Effect of particulated marrow and cancellous bone graft on healing of the bone around implants without primary bone contact

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, College of Dentistry, Korea.
  • 2Dental Science Research Institute, Chonnam National University, Korea.

Abstract

Implant stability is the key to long-term success of osseointegrated implants. To evaluate the effect of particulated marrow and cancellous bone (PMCB) graft on initial healing response of bone around resorbable blast media (RBM) implants without primary bone contact, 4 RBM implants (8 mm in length and 3.8 mm in diameter; AVANA, Osstem, Korea) were placed in the iliac crest of 2 adult mongrel dogs. In the control group, the implants were only positioned in the center of the drilled hole, while in the experimental group, the iliac PMCB taken from the opposite iliac crest was grafted to the drilled hole and condensed with the osteotome before implant installation. Fluorescent dyes were injected to observe the serial formation of the new bone in orders of tetracycline HCl (15 mg/kg), calcein blue (30 mg/kg), alizarin red (30 mg/kg) at 1, 4, and 7 weeks after placement. The dogs were sacrificed for radiologic, histologic observation and histomorphometrical evaluation at 8 weeks after placement. The radiographs were taken and the undecalcified specimens were prepared for histological and histomorphometrical evaluations of implant-bone contact. Histologically, direct bone apposition to implant surface was found in both control and experimental groups. But, maturer and denser bone and broader implant-bone contact were observed at the implantbone interface of the experimental group. Under the fluorescent microscope, thick regular yellow fluorescent areas were observed at the implant-bone interface in the experimental group, while red fluorescent areas which mean later bone apposition were found in the control group. The average implant-bone contact ratio at 8 weeks of healing was 50 +/- 10 % in the control and 68 +/- 5 % in the experimental group. There was significant difference between the two groups (p < 0.05). These results suggest that the bone healing begin earlier and be better around the implant in case of poor bone quality and without primary bone contact after PMCB graft.

Keyword

Implant; Bone healing; PMCB graft; Primary bone contact

MeSH Terms

Adult
Animals
Bone Marrow*
Dogs
Fluorescent Dyes
Humans
Tetracycline
Transplants*
Fluorescent Dyes
Tetracycline
Full Text Links
  • JKAMPRS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr