Chonnam Med J.  2006 Aug;42(2):148-152.

A Case of Acute Myocardial Infarction Associated with Graves' Disease

• Lee KW
• Kang DG
• Yun SH
• Kim JH
• Park OS
• Ko YC
• Lee SU
• Kim SH
• Cho SK

Abstract

Hyperthyroidism has cardiovascular complications such as sinus tachycardia, atrial fibrillation, congestive heart failure, angina pectoris and myocardial infarction. Among those complications, a myocardial infarction is rarely reported. We report a 52-year-old man presented with an epigastric pain. On physical examination, diffuse goiter was found on the anterior portion of the neck. His electrocardiogram showed ST elevation in leads V1 to V4 and T wave inversion in leads V1 to V5. The creatine kinase-MB level was 33 U/L and cardiac troponin I was 7.09 ng/ml. The serum levels of thyroid hormone showed T3 612 ng/dl, T4 24 microgram/dl, Free T4 4.56 ng/dl and TSH 0.001 IU/ml, with positive anti-microsomal antibody. A two-dimensional echocardiography showed an anterior septal wall hypokinesia, and a diagnostic coronary angiogram revealed significant stenosis in the proximal and middle left anterior descending artery (LAD). The proximal and middle LAD were successfullly recanalized using ballon angioplasty and stenting.

Keyword

Graves' disease; Hyperthyroidism; Myocardial infarction

MeSH Terms

Angina Pectoris
Angioplasty
Arteries
Atrial Fibrillation
Constriction, Pathologic
Creatine
Echocardiography
Electrocardiography
Goiter
Graves Disease*
Heart Failure
Humans
Hyperthyroidism
Hypokinesia
Middle Aged
Myocardial Infarction*
Neck
Physical Examination
Stents
Tachycardia, Sinus
Thyroid Gland
Troponin I
Creatine
Troponin I