J Bacteriol Virol.  2007 Sep;37(3):129-136. 10.4167/jbv.2007.37.3.129.

Chemical Composition and Antibacterial Activity Against Oral Bacteria by the Essential Oil of Artemisia iwayomogi

  • 1Institute of Oral Bioscience and Department of Oral Microbiology, School of Dentistry, Chonbuk National University, Republic of Korea. joungdan@chonbuk.ac.kr


The aerial part of Artemisia iwayomogi KITAMURA has traditionally been used for antitumour, immunomodulating, antimutagenic, antioxidant, antibacterial, antifungal, antipyretic, diuretic, liver protective effect, and choleretic purposes in Korea. The chemical composition of the essential oil obtained from A. iwayomogi was analyzed by GC/MS. The essential oil and its major compounds were tested for antibacterial activities against 15 different genera of oral bacteria. The essential oil of A. iwayomogi was rich in camphor (17.96%), 1,8-cineole (14.79%), terpinen-4-ol (3.28%), alpha-terpineol (17.60%), and beta-caryophyllene (4.05%). The essential oil of A. iwayomogi exhibited considerable inhibitory effects against all obligate anaerobic bacteria (MICs, 0.05 to 0.2 mg/ml; MBCs, 0.1 to 0.4 mg/ml) tested, while its major compounds demonstrated various degrees of growth inhibition.


Artemisia iwayomogi; Essential oil; Antibacterial activity; Minimum inhibitory concentrations/Minimum bactericidal concentrations (MICs/MBCs)

MeSH Terms

Bacteria, Anaerobic


  • Figure 1. Gas chromatography/mass spectrometric analysis of the essential oil obtained from Artemisia iwayomogi



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