J Korean Surg Soc.  2013 Jun;84(6):367-370. 10.4174/jkss.2013.84.6.367.

Adenocarcinoma arising from Meckel's diverticulum in the ileum with malrotation of the midgut

• Lee JK
• Kwag SJ
• Oh ST
• Kim JG
• Kang WK

• KMID: 1505187
• DOI: http://doi.org/10.4174/jkss.2013.84.6.367

Abstract

Meckel's diverticulum (MD) is a true congenital diverticulum that is remnant by incomplete obliteration of the omphalomesenteric duct. It is the most common congenital anomaly of the gastrointestinal tract, with an estimated prevalence of 2% (0.3% to 3% in autopsy studies). About 90% of MD occurs within 100 cm of the ileocecal valve. A primary malignant tumor arising within an MD is extremely uncommon. Malignancies are reported to account for only 0.5% to 3.2% of the complications. Carcinoids are the most common malignant tumors occurring in MD. Adenocarcinomas are extremely uncommon and very poor prognosis has been reported. We report a case of radiographically diagnosed chronic inflammatory mass caused by adenocarcinoma arising from MD in the ileum with malrotation of the midgut incidentally discovered at exploration.

Keyword

Meckel diverticulum; Adenocarcinoma; Intestinal malrotation

MeSH Terms

Adenocarcinoma
Autopsy
Carcinoid Tumor
Diverticulum
Gastrointestinal Tract
Ileocecal Valve
Ileum
Meckel Diverticulum
Prevalence
Prognosis
Vitelline Duct

Reference

1. Dumper J, Mackenzie S, Mitchell P, Sutherland F, Quan ML, Mew D. Complications of Meckel's diverticula in adults. Can J Surg. 2006. 49:353–357.

2. Stone PA, Hofeldt MJ, Campbell JE, Vedula G, DeLuca JA, Flaherty SK. Meckel diverticulum: ten-year experience in adults. South Med J. 2004. 97:1038–1041.

3. Jay GD 3rd, Margulis RR, McGraw AB, Northrip RR. Meckel's diverticulum; a survey of one hundred and three cases. Arch Surg. 1950. 61:158–169.

4. Yahchouchy EK, Marano AF, Etienne JC, Fingerhut AL. Meckel's diverticulum. J Am Coll Surg. 2001. 192:658–662.

5. Mackey WC, Dineen P. A fifty year experience with Meckel's diverticulum. Surg Gynecol Obstet. 1983. 156:56–64.

6. Ymaguchi M, Takeuchi S, Awazu S. Meckel's diverticulum. Investigation of 600 patients in Japanese literature. Am J Surg. 1978. 136:247–249.

7. Turgeon DK, Barnett JL. Meckel's diverticulum. Am J Gastroenterol. 1990. 85:777–781.

8. Dixon AY, McAnaw M, McGregor DH, Keushkerian S, Miller LK, Pierce PD. Dual carcinoid tumors of Meckel's diverticulum presenting as metastasis in an inguinal hernia sac: case report with literature review. Am J Gastroenterol. 1988. 83:1283–1288.

9. Kusumoto H, Yoshida M, Takahashi I, Anai H, Maehara Y, Sugimachi K. Complications and diagnosis of Meckel's diverticulum in 776 patients. Am J Surg. 1992. 164:382–383.

10. Ford PV, Bartold SP, Fink-Bennet DM, Jolles PR, Lull RJ, Maurer AH, et al. Procedure guideline for gastrointestinal bleeding and Meckel's diverticulum scintigraphy. Society of Nuclear Medicine. J Nucl Med. 1999. 40:1226–1232.