Korean J Ophthalmol.  2013 Feb;27(1):34-38. 10.3341/kjo.2013.27.1.34.

Long-term Results of Deep Sclerectomy with Small Collagen Implant in Korean

• Rho S
• Kang SY
• Hong S
• Seong GJ
• Jung JJ
• Kim CY

• KMID: 1501793
• DOI: http://doi.org/10.3341/kjo.2013.27.1.34

Abstract

PURPOSE
To describe the long-term results of deep sclerectomy with collagen implant (DSCI) with or without adjuvant mitomycin C in Korean patients with primary or secondary open-angle glaucoma (OAG).
METHODS
This retrospective review was comprised of 65 Korean patients who received DSCI with or without adjuvant mitomycin C due to primary or secondary OAG. Patients were followed for 72 months after surgery. Complete success was defined as intraocular pressure (IOP) <21 mmHg without medication and qualified success was defined as IOP <21 mmHg with or without medication.
RESULTS
Mean postoperative follow-up period was 53.0 +/- 16.2 months. Mean IOP was 30.5 +/- 11.7 mmHg preoperatively, 8.4 +/- 4.3 mmHg at postoperative day one and 13.4 +/- 3.8 mmHg 60 months after surgery. The mean number of glaucoma medications was decreased from 3.6 +/- 1.1 to 1.6 +/- 1.3 at 60 months after the operation. Complete and qualified success rates were 36.7% and 79.6% at postoperative 60 months, respectively (Kaplan-Meier survival curve). No shallow or flat anterior chamber, endophthalmitis, or surgery-induced significant cataract was observed.
CONCLUSIONS
The results of DSCI in Korean patients presented here seem reasonably excellent with qualified success rates of over 70% at six years with negligible complications.

Keyword

Deep sclerectomy; Koreans; Open-angle glaucoma; Small collagen implant

MeSH Terms

Adult
Anterior Chamber/*surgery
Collagen/*administration & dosage
Drug Implants/*administration & dosage
Female
Follow-Up Studies
Glaucoma, Open-Angle/physiopathology/*surgery
Humans
Incidence
Intraocular Pressure
Male
Postoperative Complications/epidemiology
Postoperative Period
Republic of Korea/epidemiology
Retrospective Studies
Sclera/*surgery
Sclerostomy/*methods
Time Factors
Treatment Outcome
Visual Acuity
Drug Implants
Collagen

Figure

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  Fig. 1 Intraocular pressure (IOP) results during follow period (mean ± SD). Preop = preoperative.

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  Fig. 2 Visual acuity results during follow period (mean ± SD). Preop = preoperative.

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  Fig. 3 Cumulative survival rates of qualified success and complete success.

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  Fig. 4 Number of antiglaucoma medications before and after deep sclerectomy. Preop = preoperative.

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  Fig. 5 Rate of conversion to other glaucoma surgery over time.

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