Korean J Gastroenterol.  2013 May;61(5):294-296. 10.4166/kjg.2013.61.5.294.

Duodenal Brunner's Gland Adenoma Presenting as Subepithelial Tumor with Internal Cystic Portion

• Choi DW
• Park SC
• Chang SJ
• Lee SJ

• KMID: 1501654
• DOI: http://doi.org/10.4166/kjg.2013.61.5.294

Abstract

No abstract available.

MeSH Terms

Adenoma/*diagnosis/pathology/ultrasonography
Brunner Glands/pathology
Duodenal Neoplasms/*diagnosis/pathology/ultrasonography
Endoscopy, Gastrointestinal
Female
Humans
Middle Aged
Tomography, X-Ray Computed

Figure

• 

  Fig. 1. Endoscopic finding. An elongated polypoid lesion with hyperemia and erosion was seen at the anterior wall of the duodenal bulb.

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  Fig. 2. Endoscopic ultrasonography finding. In the submucosal layer, about 2 cm sized elongated hyperechoic mass with internal cystic portion was noted.

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  Fig. 3. Computed tomography finding. In the coronal view, about 2 cm sized well-defined ovoid lesion of highly enhancement was seen at the duodenal bulb (arrow).

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  Fig. 4. Microscopic findings. (A) The resected specimen had internal cystic portion with thin fibrous wall (H&E, ×10). (B) It showed proliferation of Brunner's gland covered with normal duodenal mucosa (H&E, ×40).

Reference

References

1. Patel ND, Levy AD, Mehrotra AK, Sobin LH. Brunner's gland hyperplasia and hamartoma: imaging features with clinicopathologic correlation. AJR Am J Roentgenol. 2006; 187:715–722.

2. Peetz ME, Moseley HS. Brunner's gland hyperplasia. Am Surg. 1989; 55:474–477.

3. Kovacević I, Ljubicić N, Cupić H, et al. Helicobacter pylori infection in patients with Brunner's gland adenoma. Acta Med Croatica. 2001; 55:157–160.

4. Levine JA, Burgart LJ, Batts KP, Wang KK. Brunner's gland hamartomas: clinical presentation and pathological features of 27 cases. Am J Gastroenterol. 1995; 90:290–294.

5. Kang JH, Lim YJ, Hahn SJ, Choi JS, Koh MS, Lee JH. Clinical characteristics of large brunner's gland tumors in Korea. Korean J Gastrointest Endosc. 2010; 40:297–302.

6. Lee SE, Hwang DW, Lim CS, et al. The clinical features and the clinical outcome of duodenal brunner's gland adenoma. Korean J Hepatobiliary Pancreat Surg. 2008; 12:284–286.

7. Gupta V, Gupta P, Jain A. Giant Brunner's gland adenoma of the duodenal bulb presenting with ampullary and duodenal obstruction mimicking pancreatic malignancy. JOP. 2011; 12:413–419.

8. Gao YP, Zhu JS, Zheng WJ. Brunner's gland adenoma of duodenum: a case report and literature review. World J Gastroenterol. 2004; 10:2616–2617.

9. Akino K, Kondo Y, Ueno A, et al. Carcinoma of duodenum arising from Brunner's gland. J Gastroenterol. 2002; 37:293–296.

10. Brookes MJ, Manjunatha S, Allen CA, Cox M. Malignant potential in a Brunner's gland hamartoma. Postgrad Med J. 2003; 79:416–417.