Obstet Gynecol Sci.  2013 Nov;56(6):416-419. 10.5468/ogs.2013.56.6.416.

Vaginal cancer with multiple liver and pulmonary metastases that achieved long-term survival

• Kim JY
• Lee KA
• Kim BG
• Bae DS
• Lee JW

• KMID: 1500378
• DOI: http://doi.org/10.5468/ogs.2013.56.6.416

Abstract

Primary vaginal cancer represents only 1% to 2% of malignant neoplasm of the female genital tract. Here, we report a 68-year-old woman who showed a vaginal tumor extending to urethra and clitoris, a 10 cm-sized mass in left adnexa and multiple metastases in lung and liver. Vaginal biopsy showed squamous cell carcinoma of vagina and she was diagnosed as International Federation of Gynecology and Obstetrics stage IVB vaginal cancer. Palliative surgery including left salpingectomy, tumorectomy, and clitoris mass excision was performed. Concurrent chemoradiation therapy (CCRT) with six cycles of 5-fluorouracil and cisplatin was administered. The patient had a complete remission of 20 months after treatment. At a 40-month follow-up, there was no evidence of local recurrence or distant metastasis. We can suggest that CCRT is very effective in treating primary squamous cell carcinoma of the vagina, not only in locally advanced but also systemically involved vaginal cancer in selected cases.

Keyword

Chemoradiotherapy; Metastasis; Vaginal Neoplasms

MeSH Terms

Aged
Biopsy
Carcinoma, Squamous Cell
Chemoradiotherapy
Cisplatin
Clitoris
Female
Fluorouracil
Follow-Up Studies
Humans
Liver
Lung
Neoplasm Metastasis*
Palliative Care
Salpingectomy
Survivors*
Urethra
Vagina
Vaginal Neoplasms*
Cisplatin
Fluorouracil