Korean J Clin Oncol.  2019 Dec;15(2):68-71. 10.14216/kjco.19013.

Hepatic resection for isolated stomach cancer liver metastases: A single-center experience

• Kim H
• Seo HI

• KMID: 2470668
• DOI: http://doi.org/10.14216/kjco.19013

Abstract

PURPOSE
The objective of this study was to investigate the outcomes of selected patients with stomach cancer liver metastasis (SCLM) without extrahepatic metastases after hepatic resection.
METHODS
Patients whose imaging results did not detect extrahepatic disease were selected for hepatic resection. If R0 resection was possible and if the operative risk was low in the preoperative tests, the patients underwent hepatic resection.
RESULTS
Between 2011 and 2016, seven patients underwent hepatic resection for SCLM. All patients received hepatic resection to achieve an R0 resection. Minor liver resection was performed in all patients. Two patients showed long-term survival with a single lesion and human epidermal growth factor receptor 2 (HER2)-negative tumor. The 5-year overall survival and disease-free survival rates after hepatic resection were 38.1% and 28.6%, respectively.
CONCLUSION
Hepatic resection for isolated SCLM may be considered as a multimodality treatment. However, it has only limited benefits in select patients. It has long-term survival benefit in patients with single metastases and HER2-negative hormonal status.

Keyword

Liver resection; Liver metastases

MeSH Terms

Disease-Free Survival
Humans
Liver*
Neoplasm Metastasis*
Receptor, Epidermal Growth Factor
Stomach Neoplasms*
Stomach*
Receptor, Epidermal Growth Factor