J Biomed Res.
2013 Jun;14(2):128-131.
A case of metastatic cholangiocarcinoma in a ferret
- Affiliations
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- 1Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea. jeongks@knu.ac.kr
- 2Stem Cell Therapeutic Research Institute, Kyungpook National University, Daegu 702-701, Korea.
Abstract
- Cholangiocarcinoma is a relatively rare neoplasm in animals and humans. A four-year-old, neutered male ferret presented with depression, anorexia, cachexia, diarrhea, and icterus. Necropsy findings included ascites, multiple white nodules on the surface of the liver, stomach, and duodenum, gross enlargement of the bile duct and right atrium, hemorrhage of the gastric and duodenal mucosa, and icterus of the mesenteric fat. Infiltrative well-differentiated neoplastic biliary epithelial cells forming ducts and acini with a prominent collagenous stroma were observed on microscopic examination of neoplastic lesions within the liver, mesentery, and the serosa of the stomach and duodenum. This is a report on a rare case of obstructive jaundice due to cholangiocarcinoma in a ferret.
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