Korean J Dermatol.
2008 Sep;46(9):1292-1295.
A Case of Benign Cephalic Histiocytosis
- Affiliations
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- 1Department of Dermatology, School of Medicine, Medical Research Institute, Chungbuk National University, Cheongju, Korea. tyyoon@chungbuk.ac.kr
- 2Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
Abstract
- Benign cephalic histiocytosis is a rare non-Langerhans histiocytosis, which typically presents as a benign self-healing eruption of papules on the head and neck of infants and young children. We report the case of a 13-month-old boy who presented with many reticulated erythematous papules and macules on the face. The histologic examination showed relatively well-circimscribed band-like interstitial and perivascular infiltration of histiocytes, with vesicular nuclei and ample cytoplasms in the upper dermis. Immunohistochemically, the histiocytes were positive for CD68 while lacking expression of CD1a. Approximately 1 year after the first visit, the facial papules became flattened and hyperpigmented.
