J Korean Soc Ultrasound Med.  2008 Sep;27(3):125-130.

Sonohysterography-Guided Biopsy of Focal Endometrial Lesions: Value of Four-dimensional Ultrasonography

• Kim JM
• Lee EJ
• Kim JK
• Joo HJ

Abstract

PURPOSE: To assess the usefulness of four-dimensional (4D) ultrasonographic guidance in sonohysterographyguided biopsy of focal endometrial lesions.
MATERIALS AND METHODS
Endometrial biopsies were performed prospectively under 4D ultrasound guidance in 24 consecutive patients with focal endometrial lesions detected on baseline sonohysterography. A single slice view in three orthogonal planes, a sagittal surface-rendered image, and multislice views in the sagittal plane were used for real-time guidance during the procedure. We evaluated feasibility based on the technical success rates and the number of "diagnostic" specimens obtained for histological diagnosis, and we correlated the biopsy results with the pathological diagnosis determined through the surgical procedure.
RESULTS
Four-dimensional sonohysterography-guided biopsy was successfully performed in 21 (87.5%) of 24 patients without any significant complication. The biopsy specimens were diagnostic in 19 (90.5%) of 21 patients. Thirteen of 19 patients (68.4%) patients underwent surgery, and the diagnoses obtained using cytology correlated well with the pathology.
CONCLUSION
Four-dimensional ultrasonography-guided biopsy is technically feasible and may be useful in the diagnosis of focal endometrial lesions.

Keyword

Ultrasound (US); Uterus, biopsy; Uterus, endometrium; Uterine neoplasm

MeSH Terms

Biopsy
Humans
Prospective Studies
Uterine Neoplasms