J Korean Endocr Soc.
2008 Jun;23(3):210-214. 10.3803/jkes.2008.23.3.210.
A Case of Intravenous Pamidronate-Related Osteonecrosis of the Jaw in a Patient with Waldenstrom's Macroglobulinemia
- Affiliations
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- 1Department of Endocrinology and Metabolism, Ajou University School of Medicine, Korea.
- 2Department of Hematology-Oncology, Ajou University Schoo of Medicine, Korea.
- 3Department of Dentistry, Ajou University School of Medicine, Korea.
- 4Department of Pathology, Ajou University School of Medicine, Korea.
- KMID: 1479209
- DOI: http://doi.org/10.3803/jkes.2008.23.3.210
Abstract
- Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare, but serious, side effect of bisphosphonate therapy that produces significant morbidity in affected patients. It is characterized by poor wound healing and spontaneous intra-oral soft tissue breakdown, which lead to exposure of necrotic maxillary and mandibular bone.
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