Nucl Med Mol Imaging.  2009 Dec;43(6):596-599.

Camurati-Engelmann's Disease on (99m)Tc-MDP Bone Scan

• Yoon HJ
• Oh SW
• Paeng JC
• Lee Y
• Choi IH
• Lee DS

Abstract

A 24 year-old female presented for a (99m)Tc-methylene diphosphonatae (MDP) whole body bone scan due to chronic pain in the bilateral lower extremities that has aggravated since 2002. She was diagnosed with Camurati-Engelmann disease (CED) based on the clinical and radiological findings in 2002, and she re-visited our institute to evaluate disease status at this time. CED is a rare autosomal dominant type of bone dysplasia characterized by progressive cortical thickening of long bones, and narrowing of medullary cavity, and thus presents with typical clinical symptoms and signs such as chronic pain in the extremities, muscle weakness, and waddling gait. On the (99m)Tc-MDP bone scan performed to evaluate disease status, intense increased uptake was seen in the skull, facial bones, bilateral scapulae, bilateral long bones, and bilateral pelvic bones, which clearly demonstrated the extent of CED involvement.

Keyword

Camurati-Engelmann's disease; (99m)Tc-MDP bone scan

MeSH Terms

Bone Diseases, Developmental
Camurati-Engelmann Syndrome
Chronic Pain
Extremities
Facial Bones
Female
Gait
Humans
Lower Extremity
Muscle Weakness
Pelvic Bones
Scapula
Skull