Nucl Med Mol Imaging.  2010 Jun;44(2):146-149.

Diffuse Pulmonary Uptake of Tc-99m Methylene Diphosphonate in a Patient with Non-tuberculosis Mycobacterial Infection

Affiliations
  • 1Department of Nuclear Medicine, Seoul National University College of Medicine, 28 Yeongeon-dong Jongno-gu, Seoul, Korea. jkchung@plaza.snu.ac.kr
  • 2Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Radiology, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Abstract

Extra-osseous uptake of bone-seeking radiopharmaceuticals has been reported at various sites and it is known to be induced by various causes. Diffuse pulmonary infection, such as tuberculosis, can be a cause of lung uptake of bone-scan agent. Here we report on a patient with non-tuberculosis mycobacterial infection (NTM) who demonstrated diffuse pulmonary uptake on Tc-99m MDP bone scan. After medical treatment for NTM, the patient's lung lesions improved. Extraskeletal lung Tc-99m MDP uptake on bone scan may suggest lung parenchymal damage associated with disease activity.

Keyword

Diffuse pulmonary uptake; Tc-99m MDP; Non-tuberculous mycobacterium

MeSH Terms

Diphosphonates
Humans
Lung
Radiopharmaceuticals
Technetium Tc 99m Medronate
Tuberculosis
Diphosphonates
Radiopharmaceuticals
Technetium Tc 99m Medronate
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